return icon Vietnamnet.vn

Ebola vaccine 'promising' say scientists after human trial

 The first human trial of an experimental vaccine against Ebola suggests that it is safe and may help the immune system to combat the virus.

The first human trial of an experimental vaccine against Ebola suggests that it is safe and may help the immune system to combat the virus.

{keywords}

A 39-year-old woman was the first volunteer to receive the experimental Ebola vaccine

 

Twenty volunteers were immunised in the United States. Scientists at the US National Institutes of Health (NIH) described the results as "promising".

The research is published in the New England Journal of Medicine (NEJM).

None of those immunised suffered major side-effects and all produced antibodies.

Dr Anthony Fauci of the NIH told the BBC: "On safety and on the ability to produce an appropriate immune response we can call this trial an unqualified success, even though it was an early Phase One trial."

The volunteers were divided into two groups, receiving either a low or high dose. The antibody response was stronger among those receiving the higher dose.

The investigators found that seven of the high dose and two of the lose dose volunteers produced T-cell immune responses, which may be important in protection against Ebola viruses.

The vaccine uses a chimpanzee cold virus which has been genetically engineered to carry a non-infectious Ebola protein on its surface.

There are four trials underway of this experimental vaccine.

The US vaccine is bivalent - aimed at giving protection against the Sudan and Zaire strains of Ebola. It is the latter which is responsible for the current outbreak.

Trials of a monovalent vaccine - against the Zaire strain - are also underway in Oxford, Mali and Switzerland.

If these also yield positive results then the monovalent vaccine will be offered to thousands of health workers in west Africa.

Dr Fauci said: "It will be this large Phase Two / Three trial in west Africa which will show whether the vaccine works and is really safe."

He added: "If the outbreak is still is still going on six months from now and the vaccine at that point is shown to be effective, it could have a very positive impact on the current epidemic."

But he said the long-term aim was to produce a vaccine which would protect against future outbreaks.

If the vaccine does work, it is unclear how long the protection would last.

Indemnity agreement

These kinds of questions are usually settled during the early stages of human trials.

But such is the pressing humanitarian need for something which protects against Ebola, the whole trial process is being accelerated at unprecedented speed.

{keywords}

A health worker in Conakry, Guinea, wearing protective clothing to treat victims

 

 

In an editorial in the NEJM Dr Daniel Bausch said that while the trial left many questions unanswered, an Ebola vaccine was "one step closer".

The experimental vaccine is being manufactured by the British drugs giant GlaxoSmithKline (GSK).

The company says it can produce one million doses a month by the end of 2015.

This will require a significant financial outlay. It is asking for an indemnity agreement in case problems such as unforeseen side effects were to emerge in the future.

GSK's chief executive Sir Andrew Witty told the BBC: "We are not waiting for that to be settled [but] it is obvious there are some risks that companies should not be expected to carry on their own."

Source: BBC

MORE NEWS

Hanoi to turn middle alluvium ground into park

One more park has been designed for Hanoians. However, it is still unclear when the project will appear, as a number of other projects are still on paper or pending.

Asian investors eye more M&A opportunities in Vietnam

Investors from Japan, the Republic of Korea (RoK), and Singapore are looking for more potential merger and acquisition (M&A) opportunities in Vietnam, pinning high hopes on the long-term growth prospects of the market.

Vietnam's fishery exports exceed 10 billion USD in 11 months

Fishery exports reeled in 10.14 billion USD as of November this year, up 27% annually, said the Ministry of Agriculture and Rural Development.

HCM City want foreign doctors to be fluent in Vietnamese

The HCM City Department of Health has just proposed that foreign doctors should be fluent in Vietnamese if they want to work in the country.

Use of toxic e-cigarettes among students on the rise

After a trial smoke, T lost consciousness, was foaming at the mouth, and his limbs were curled up. Two days later, T regained consciousness at the hospital, but was still in the status of extreme fear.

Vietnam spends US$7.74 billion importing petroleum products

Vietnam imported over 7.5 million tonnes of oil and petrol worth around US$7.74 billion as of mid-November, up 24.1% in volume and 122% in value year on year, according to the General Department of Vietnam Customs.

Vietnam won’t sacrifice the environment for economic growth: Prime Minister

Vietnam takes people as the goal in development. People will enjoy the fruits of a green economy and the government will not sacrifice the environment to pursue economic growth.

Vietnam’s bond market contracts amid monetary tightening

After strong growth in the previous quarter, Vietnam’s currency bond market contracted 0.2% due to a decline in the Government bond market and slower growth in corporate bonds.

AI used to predict renewable-energy capacity

Wind and solar power will account for an increasing proportion of Vietnam’s total electricity capacity.

Infrastructure pinpointed to spur socioeconomic fortunes

The Vietnamese government is continuing to promote infrastructure development with the construction of expressways and new bridges, in efforts to spur socioeconomic development and welcome new private investment.

Budget resolutions set plan for 2023

Vietnam’s state budget performance is expected to see a deficit of billions of US dollars this year, with such a landscape fixed for next year – with warnings sounded about punishing violations in budget management and usage.

Vietnam fruit exported to new markets

2022 has been a successful export year as Vietnam’s farm produce has accessed many international markets.

Colourful beauty of Lo Lo ethnic costumes

Living at the foot of Rong (Dragon) Mountain in Lung Cu Commune, Dong Van District, Ha Giang Province, the Lo Lo ethnic community have effectively preserved their traditional culture, including their attire.

Sapa forecasted to experience frost

Mount Fansipan in the northern province of Lao Cai’s Sapa Town has been forecasted to see frost in the coming days as temperatures fall below zero degrees centigrade.

Dortmund footballers excited to discover Hanoi

Following their arrival in Hanoi, players of Bundesliga FC Borussia Dortmund enjoyed a cyclo tour around the Vietnamese capital and explored some famous sightseeing spots ahead of their friendly match against hosts Vietnam on November 30.
back_to_top