Vietnam tests Covid-19 herbal medicine on 260 patients

A locally developed Covid-19 treatment drug called Vipdervir will be tested on 260 Covid-19 patients.

Vietnam tests Covid-19 herbal medicine on 260 patients

Dr. Le Quang Huan (right) and his colleagues during preclinical research on the Vipdervir drug.

The Vietnam Academy of Science and Technology has announced the results of preclinical research on a Covid-19 treatment drug called Vipdervir, which is made entirely from Vietnamese herbs. The project is chaired by Assoc. Prof. Dr. Le Quang Huan, a senior researcher at the Institute of Biotechnology under the Vietnam Academy of Science and Technology.

The National Ethics Council for Biomedical Research, Ministry of Health has praised the results of preclinical studies and approved the clinical trial of Vipdervir on Covid-19 patients.

The Ministry of Health will coordinate with the Vietnam Academy of Science and Technology to direct relevant agencies to conduct clinical trials on 260 Covid-19 patients. If the clinical trial results are safe and effective, the Administration of Traditional Medicine and Pharmacy will consider licensing the drug.

Dr. Nguyen Ngo Quang, Deputy Director of the Department of Science and Technology Training, Ministry of Health says that the advantage of the clinical trial process is that the number of Covid-19 patients, especially those with mild and moderate symptoms, is very large, so the recruitment of volunteers to participate in the study is convenient. Secondly, Vipdervir is completely made of herbs, which is a traditional medicine product, so many people want to use it.

The clinical research period is scheduled to be about 2-3 months, and then an additional 1-2 months are needed for scientists to summarize the research.

"We hope this product will be licenced by the end of this year," said Dr. Nguyen Ngo Quang.

The results of preclinical studies show that Vipdervir is safe and effective in inhibiting the growth of SARS-CoV-2 virus, enhancing immunity in experimental models.

 

According to Dr. Le Quang Huan, the research team used bioinformatics technology to screen the main active ingredients in herbs with strong binding affinity to molecules involved in the invasion and proliferation of the SARS-CoV-2 virus. They also combined ancient and modern medical documents and recent international publications to create a product with the highest treatment efficiency.

On that basis, Vipdervir can prevent the adhesion of the virus to the host cell, and inhibits viral replication while activating immune cells so that they recognize, block and eliminate viral particles. These mechanisms have a synergistic effect to help prevent and treat Covid-19.

In a preclinical study on rabbits, after giving rabbits an oral suspension with two doses of 0.378 tablets/kg rabbit/day for 28 consecutive days (equivalent to the maximum dose for a human of 6 tablets/person/day) and 1.133 tablets/kg of rabbit/day (3 times higher than the maximum dose for a human), the test sample did not affect the weight, body condition and movement of the rabbits.

The rabbits were healthy with no difference in their weight before, between and after the test.

Vipdervir has been evaluated for toxicity at the Pharmacology Faculty of the Hanoi Medical University and the Central Institute for Drug Testing. It was evaluated for the ability to inhibit H5N1 virus at the Institute of Biotechnology, and evaluated for the ability to inhibit SARS-CoV-2 virus at the Central Institute of Hygiene and Epidemiology.

Nguyen Lien

Remdesivir approved for COVID-19 treatment in Vietnam

Remdesivir approved for COVID-19 treatment in Vietnam

The first 50,000 vials of Remdesivir from India arrived in Tan Son Nhat Airport, Ho Chi Minh City on Thursday (August 5) and another 40,000 vials arrived on Friday night.

Traditional medicine used to treat Covid-19 patients

Traditional medicine used to treat Covid-19 patients

The Ministry of Health (MOH) has allowed the use of xuyen tam lien (Andrographis paniculata), a familiar traditional medicine, in Covid-19 treatment, according to Luong Ngoc Khe, Director of the Administration of Medical Examination and Treatment.

 
 

Other News

.
Aviation authority proposes to scrap rapid testing in favour of RT-PCR
Aviation authority proposes to scrap rapid testing in favour of RT-PCR
SOCIETYicon  06/01/2022 

The Civil Aviation Authority of Vietnam (CAAV) wants arriving passengers tested for SARS-CoV-2 following the RT-PCR method prior to their flight, removing the additional need for rapid testing as well. 

Unknown man calls Vietnam Airlines, threatens to shoot down plane heading to Hanoi from Japan
Unknown man calls Vietnam Airlines, threatens to shoot down plane heading to Hanoi from Japan
SOCIETYicon  06/01/2022 

An anonymous man called a Vietnam Airlines branch in Japan on Wednesday morning, and said that if a flight heading from Narita (Japan) to Hanoi did not turn back it would be shot down, according to the Civil Aviation Authority of Vietnam (CAAV).

Medicines with molnupiravir for COVID-19 treatment proposed to be licensed
Medicines with molnupiravir for COVID-19 treatment proposed to be licensed
SOCIETYicon  06/01/2022 

An advisory council of the Ministry of Health (MoH) has proposed this ministry grant certificates of registration for conditional circulation of three medicines containing the active ingredient molnupiravir for COVID-19 treatment.

Sale of unauthorised COVID-19 treatment drugs on the rise across social media
Sale of unauthorised COVID-19 treatment drugs on the rise across social media
SOCIETYicon  06/01/2022 

As the battle against COVID rages on, some are taking advantage of the anxiety and worry of others to make a fast buck, no matter the consequences. 

After 30 years, Vietnam's fertility rate drops by nearly half
After 30 years, Vietnam's fertility rate drops by nearly half
SOCIETYicon  05/01/2022 

Over the past 30 years, Vietnam's fertility rate has fallen dramatically. The total fertility rate (TFR) fell from 3.8 children/woman in 1989 to 2.09 children/woman in 2019.

Local Molnupiravir manufacturers to be licensed soon
Local Molnupiravir manufacturers to be licensed soon
SOCIETYicon  05/01/2022 

Health professionals of the Ministry of Health are due to meet on January 5 to consider licensing local pharmaceutical companies that produce Molnupiravir for COVID-19 treatment.

Ho Chi Minh City to reopen bars, dance clubs from next week
Ho Chi Minh City to reopen bars, dance clubs from next week
SOCIETYicon  05/01/2022 

Ho Chi Minh City will reopen bars, dance clubs and karaoke parlors from January 10 after a period of suspension due to the COVID-19 pandemic.

Resolution 128 a game changer in Vietnam’s COVID-19 fight
Resolution 128 a game changer in Vietnam’s COVID-19 fight
SOCIETYicon  05/01/2022 

Resolution 128 is of great significance in COVID-19 fight and economic recovery, Deputy Minister of Planning and Investment Tran Quoc Phuong said.

Oodles of glass noodles ready for Tet at So Village
Oodles of glass noodles ready for Tet at So Village
SOCIETYicon  05/01/2022 

The canna noodles, or glass noodles, of So Village in Tan Hoa Commune, Quoc Oai District, have long been known as a specialty of the Hanoi countryside, loved far and wide. They are probably the most famous noodles in the country.

New policies in 2022: pensions go up slightly, petrol prices increase sharply
New policies in 2022: pensions go up slightly, petrol prices increase sharply
FEATUREicon  06/01/2022 

Some new policies affecting most residents in the country take effect in January 2022.

HCM City issues quarantine procedure for arrivals in face of Omicron
HCM City issues quarantine procedure for arrivals in face of Omicron
SOCIETYicon  04/01/2022 

HCM City People’s Committee has just issued urgent guidelines for a five-step quarantine procedure for arriving passengers amid the emergence of the Omicron variant in Vietnam.

VIETNAM NEWS HEADLINES JANUARY 5
VIETNAM NEWS HEADLINES JANUARY 5
SOCIETYicon  05/01/2022 

Vietnam secures over 195 million doses of vaccines against COVID-19

VN to remedy all dioxin hot spots by 2030: National plan
VN to remedy all dioxin hot spots by 2030: National plan
SOCIETYicon  03/01/2022 

Prime Minister Pham Minh Chinh has signed Decision No. 2215/QD-TTg on the national action plan on overcoming the post-war consequences of toxic chemicals/dioxin in Vietnam for 2021-30.

National strategy aims to provide clean water to rural residents by 2030
National strategy aims to provide clean water to rural residents by 2030
SOCIETYicon  03/01/2022 

Deputy Prime Minister Le Van Thanh signed a decision approving the National Rural Clean Water Supply and Sanitation Strategy by 2030, with a vision to 2045.

VIETNAM NEWS HEADLINES JANUARY 3
VIETNAM NEWS HEADLINES JANUARY 3
SOCIETYicon  03/01/2022 

Vietnam looks to master technology in renewable energy

Vietnamese-origin professor knighted by Queen Elizabeth II
Vietnamese-origin professor knighted by Queen Elizabeth II
SOCIETYicon  03/01/2022 

Professor Jonathan Van-Tam, Deputy Chief Medical Officer for England, has been freshly knighted by the Queen Elizabeth II of the UK for his contributions to the local fight against COVID-19.

Ho Chi Minh City confirms five Omicron cases
Ho Chi Minh City confirms five Omicron cases
SOCIETYicon  02/01/2022 

Five cases of the Omicron variant of COVID-19 have been detected in Ho Chi Minh City, according to the municipal Department of Health.

Over 14,800 new Covid infections reported
Over 14,800 new Covid infections reported
SOCIETYicon  01/01/2022 

The Ministry of Health this evening, January 1 confirmed 14,835 fresh Covid cases, with 13 of them imported and 14,822 locally infected in 62 cities and provinces, dipping by 1,654 cases over yesterday.

Students of grades 7, 8, 9, 10, 11, 12 to go to schools in person in HCMC
Students of grades 7, 8, 9, 10, 11, 12 to go to schools in person in HCMC
SOCIETYicon  01/01/2022 

The People's Committee in HCMC directed educational institutions to provide face-to-face teaching for students in grades 7, 8, 9, 10, 11 and 12 from January 4, 2022.

More officials investigated for COVID-19 test kit overcharging
More officials investigated for COVID-19 test kit overcharging
SOCIETYicon  01/01/2022 

Several suspects in the overcharging for COVID-19 test kits at the Viet A Technologies JSC are being investigated for “offering bribe”, “receiving bribe”, and “abusing position and power while performing duties”.

 
 
 
Leave your comment on an article

OR QUICK LOGIN