return icon Vietnamnet.vn

Made-in-Vietnam Nanocovax is expected to be as good as foreign vaccines

The test of locally-made Nanocovax vaccine has yielded positive signs. In case of emergency approval, Vietnam would be able to produce 100 million doses per year.

Nanocovax of Nanogen Pharmaceutical Biotechnology JSC is currently Vietnam's Covid-19 vaccine with the most potential. This vaccine is now in the third phase of trial, with the participation of 1,000 volunteers. So far, only 1 case of grade 2 anaphylactic reaction has been recorded, and this volunteer has fully recovered.

In phase 1-2 trials, Nanocovax vaccine was proven to be effective against the British and South African virus strains. Nanocovax is expected to be as good as foreign vaccines. If this vaccine is approved for use, Nanogen can produce 100 million doses per year.

 

Kết quả thử nghiệm vắc xin Nanocovax, nhiều tín hiệu khả quan

Volunteers participating in the phase 3 trial of Nanocovax vaccine at the Military Medical Academy. Photo: Pham Hai

 

 

In the first two phases of trial, 100% of the volunteers had good immunity, and the seroconversion rate reached 99.4%, compared to 91-96% for Pfizer, 100% for Moderna, and 96-100% for Novavax - another Made-in Vietnam vaccine. The rate of side effects of Nanocovax is even lower than that of Pfizer and Moderna.

Nanocovax is currently one of 15 Covid-19 vaccines under Phase 3 clinical trial in the world.

General Director of Nanogen, Mr. Ho Nhan, said that in April 2020, the selection of vaccine production technology in the early stages was extremely difficult. However, it took Nanogen only one week to come up with the design idea.

At that time, the world was developing four technologies: mRNA, vector virus, inactivated virus and recombinant protein. The vaccines like Pfizer and Moderna use the latest technology - mRNA. Nanogen chose the technology it knows the best and are most confident about - recombinant protein.

"We use artificial intelligence with the support of leading robots in biotechnology research to help create fake spikes faster," Nhan said.

It took the research team a lot of time to fine-tune the gene segments as the virus constantly mutated to make the vaccine effective.

Recombinant protein technology has been used by Nanogen for more than 10 years, applied on bioequivalent drugs such as Nanokine, Pegnano, Pegcyte and Trastuzumab to treat anemia, cancer and other diseases.

The research team with more than 500 members began making the vaccine, with 300 people directly involved. After more than seven months, on December 17, 2020, Nanocovax started the phase 1 clinical trial and in June 2021, it launched the third phase trial.

Nanogen’s research director Do Minh Si added that while vaccines using mRNA technology such as Pfizer and Moderna use hundreds of materials sourced from dozens of countries, including many rare materials, Nanocovax uses a more common technology so its source of raw materials is stable.

The company has had a modern closed production line, with current capacity of 8 million doses per month. After being upgraded in August, the capacity will increase to 10 million doses per month.

Nanogen is building a cold storage system with a capacity of 10 million doses and 5 refrigerated trucks carrying vaccines at 2-8 degrees Celsius.

The estimated price for Nanocovax is VND130,000 – VND230,000 per dose (US$$4-$10).

Thuy Hanh

Vietnam may grant emergency license for locally-made Covid-19 vaccine

Vietnam may grant emergency license for locally-made Covid-19 vaccine

Soon after the phase 3 trial, Vietnam may consider emergency licensing for Nanocovax, a made-in-Vietnam Covid-19 vaccine.

 

MORE NEWS

Former State President Nguyen Xuan Phuc explains his resignation

Former President Nguyen Xuan Phuc decided to resign and retire as he was fully aware of his responsibilities before the Party and the people when a number of officials under him committed violations during his stint as prime minister in 2016-2021.

Vietnam remains third largest seafood supplier to RoK

The nation remained the third largest seafood supplier to the Republic of Korea (RoK) last year with the country’s seafood market share as part of the RoK’s total imports reaching 10.2%, according to statistics released by the Korea Customs Service.

Airline agencies asked to tighten control over smuggling by air

The Civil Aviation Administration of Vietnam (CAAV) has asked agencies under its wing to strengthen inspection and supervision to promptly detect and handle smuggling by air.

Vietnamese FM meets Cambodian, Philippine, Malaysian counterparts

Foreign Minister Bui Thanh Son met with his Cambodian, Philippine and Malaysian counterparts on February 3 on the sidelines of the 32nd ASEAN Coordinating Council Meeting (ACC-32) in Jakarta, Indonesia.

Vietnam to help Timor Leste soon become official member of ASEAN: FM

Vietnam will work with other ASEAN member states to discuss, agree on processes, procedures and necessary measures to support Timor Leste to become an official member of the group soon, Foreign Minister Bui Thanh Son said.

Vietnamese circus artists Quoc Co, Quoc Nghiep set new world record

Circus artists Giang Quoc Co and Giang Quoc Nghiep on February 3 (Vietnam time) set a new head-to-head balancing walk plus blindfold record in Milan, Italy.

HCM City faces shortage of teachers at all levels

The Ho Chi Minh City People’s Committee has held a press conference to provide information about socioeconomic issues and epidemic prevention and control in the city.

Female People's Army officer works at EU Training Mission in Africa

Of the seven officers of the Vietnam People’s Army sent by the President to international missions, Lieutenant Colonel Vu Thi Lien is the first officer performing duties at the European Union Training Mission in Central African Republic (EUTM RCA).

VIETNAM NEWS HEADLINES FEBRUARY 4/2023

Minister requests fruitful cooperation in defence industry with other countries

Vietnamese cyber users advised to be cautious about ChatGPT registration

ChatGPT has recently been so popular in various fields. Since there are limits in ChatGPT registration from Vietnam, Internet users here are warned to be careful to proceed with the process to avoid being scammed.

2-3 more submarine fiber cable routes needed for Vietnam

The Vietnam Internet Association’s (VIA) Secretary General Vu The Binh said Vietnam needs at least two or three more submarine fiber cable routes in the next five years to serve mounting demand.

Vietnam still approves use of Covid antibody treatment

Vietnam still approves use of Covid antibody treatment Evusheld as it is still effective against subvariants circulating in the Southeast Asian country.

Former Coast Guard generals accused of embezzling $2.1 million

The crime allegedly started in 2019 when the Vietnam Coast Guard’s Department of Technology was allocated VNĐ150 billion (US$6.3 million) to purchase equipment.

Transport Ministry told to disburse VND94 trillion in 2023

The Government has tasked the Ministry of Transport with disbursing nearly VND94.2 trillion of public investment in 2023, up 1.7-fold against the 2022 figure and 2.2-fold versus 2021.
back_to_top